Elevated S100A9 expression in chronic rhinosinusitis coincides with elevated MMP production and proliferation in vitro
نویسندگان
چکیده
منابع مشابه
Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps
BACKGROUND Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by type 2 inflammation with high levels of Th2 cytokines. Although T helper cytokines are released from T cells, innate lymphoid cells (ILC) are also known to produce high levels of the same cytokines. However, the presence of various types of ILC in CRS is poorly understood. OBJECTIVE The objective of this st...
متن کاملElevated Highways in Residential Layouts: The Imposed Negative Impacts (Case Study: Sadr Elevated Highway)
Fast growing population, excessive expansion of cities, and dominance of automobile in urban life have troubled cities with complicated traffic problems. In many parts of the world, transport network development has always been considered as a solution for this problem. Apparently, one-dimensional ‘traffic solutions’ would never thoroughly bring best results as the city and its problems are com...
متن کاملCHRONIC OBSTRUCTIVE PULMONARY DISEASE Elevated MMP-12 protein levels in induced sputum from patients with COPD
Background: Several matrix metalloproteinases (MMPs) are involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). In mice, MMP-12 plays a crucial role in the development of cigarette smoke induced emphysema. A study was undertaken to investigate the role of MMP-12 in the development of COPD in human smokers. Methods: Induced sputum samples were collected from patients with ...
متن کاملElevated Fis expression enhances recombinant protein production in Escherichia coli.
A genetic strategy to enhance recombinant protein production is discussed. A small DNA bending protein, Fis, which has been shown to activate rRNA synthesis upon a nutrient upshift, was overexpressed in E. coli strain W3110 carrying vector pUCR1. Overexpression of Fis during exponential growth was shown to activate rrn promoters to different extents. A 5-fold improvement in chloramphenicol acet...
متن کاملExpression of Vascular Endothelial Growth Factor in Nasal Polyp and Chronic Rhinosinusitis
Background: Nasal inflammatory disorders such as chronic rhinosinusitis and nasal polyp are among the most prevalent complications with high socioeconomic costs. Vascular Endothelial Growth Factor (VEGF) plays a key role in angiogenesis and cell proliferation. In the present study the effect of VEGF on the development and prognosis of chronic rhinosinusitis and nasal p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-73480-8